The ClonePix® 2 Mammalian Colony Picker is a fully automated system for selecting high-value clones used in antibody discovery and cell line development. Screen more clones in less time with monoclonal verification on day zero, then screen and identify for highest producers in weeks, not months.
Hybridomas, CHO cells, stem cells and other cell types are imaged and selected based on user-defined parameters. Plate handling, barcode reading, and picking are fully integrated, and all data, including images, are saved for downstream analysis. The picker increases the probability of finding optimally produced cell lines and significantly reduces time and labor.
Key features include:
- Multiple detection methods: White light identifies and measures clone morphology, size and proximity. Fluorescence indicates expression level and/or specificity. Up to five fluorescent filters are available for multiplexing.
- Sterility maintenance: A host of sterility features and options including a UV light process for sanitizing the interior of the instrument, as well as pin washing and halogen drying are standard.
- Integrated plate storage: Includes two storage stacks for source and destination plates, each with a capacity of 10 plates.
- Discrete colony formation: Semi-solid CloneMedia™ encourages single cells to grow into discreet colonies, and allows for ease of plating. The media allows for a higher density of clones to be screened.
Animal-free media and reagents: Chemically defined and animal-free, CloneMedia cell-culture media, is optimized to increase productivity and aid in visualizing secreted antibodies when used with the CloneDetect detection agent.
Instructional Documentation: