The MinION MK1c nanopore sequencer utilizes nanopore sequencing technology. This innovative approach involves guiding DNA through nanoscale pores under an electric field, detecting unique physical changes. It offers significant advantages to researchers:
- Sequence any DNA/RNA fragments ranging from short to ultra-long lengths.
- Characterization of extensive genetic variations, adaptable to diverse applications.
- Direct sequencing of native DNA/RNA, facilitating methylation analysis.
- Real-time data availability for immediate insights and responsive analyses.
- Scalable from portable to high-throughput desktop devices, enabling sequencing anywhere.
- Cost-effective with no initial capital investment required.
- Simple, rapid, or automated library preparation methods, ensuring ease of use.
The MinION MK1c nanopore sequencer can yield up to 50 Gb of data from a single flow cell over a 72 hour run at a rate of 420 bases per second. Actual outputs may vary depending on library types and run conditions.